Liu JQ, et al. - In the present study, researchers investigated the features and risk factors for cisplatin-induced acute kidney injury (CIA) in the elderly as well as potential methods to reduce CIA. From January 1, 2013 to December 31, 2015, study participants ≥ 18 years old, with primary tumors who received initial cisplatin chemotherapy and whose serum creatinine (SCr) values were measured within 2 weeks pre- and postcisplatin treatment and who had complete medical records were chosen from a single center. As compared to younger patients, the incidence of CIA in the elderly was higher. Independent risk factors for CIA in the elderly were angiotensin-converting enzyme inhibitor/angiotensin receptor blocker usage and administration of a single application of cisplatin.