Fernandez-Alvira JM, Fernandez-Jiménez R, de Miguel M, et al. - This study sought to ascertain the long-term sustainability of a one-year peer-group-based intervention focused on cardiovascular (CV) health and behavior. Researchers included a total of 543 adults aged 25 to 50 years with at least 1 CV risk factor, received initial training through workshops, and were then assigned randomly in a ratio 1:1 to a peer-group–based intervention group (IG) or a self-management control group (CG) for 12 months. The results of this study indicate that a one-year peer-group-based intervention demonstrated favorable results at immediate post-intervention but did not indicate significant differences between the IG and CG at 52 months. It has been considered that combination of an initial training period (workshops) with the maintenance of peer-support groups or other re-intervention strategies may be required to achieve sustained effects on healthy behaviors.