The calreticulin (CALR) exon 9 mutations are promising targets for cancer immune therapy
Leukemia Aug 31, 2017
Holmström MO, et al. – Here the scientists illustrated that CALR–mutant (CALRmut)–specific T cells were able to specifically recognize CALRmut cells. The CALR exon 9 mutations were targets for specific T cells. Hence, they were promising targets for cancer immune therapy such as peptide vaccination in patients harboring CALR exon 9 mutations.
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