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The C-reactive protein to albumin ratio predicts acute kidney injury in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Heart, Lung, and Circulation Oct 20, 2019

Karabağ Y, Çağdaş M, Rencuzogullari I, et al. - Researchers reviewed 815 consecutive patients with ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI) to determine whether there is a link between C-reactive protein (CRP) to albumin ratio (CAR])—a newly introduced inflammation-based risk score—and acute kidney injury (AKI). AKI development was reported in 110 (13.5%) patients. Higher in-hospital mortality rate was observed in patients with AKI vs those without AKI. Significantly higher mean value of CRP and CAR and lower mean levels of albumin were observed in patients with AKI vs those without AKI. The identified independent predictors of AKI included age, diabetes, hematocrit, left ventricular ejection fraction, hypotension, and CAR. Overall, the possible utility of CAR as a predictor of AKI development in STEMI patients treated with pPCI was suggested.

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