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The best way to assess oedema using T1, T2 mapping or three-dimensional T2-weighted fast-spin-echo triple inversion recovery sequences via cardiovascular MRI in outpatients with suspected myocarditis

Clinical Radiology Feb 29, 2020

Jeserich M, et al. - Researchers tried to find out T1-, T2 mapping, and a three-dimensional (3D) T2-weighted fast-spin-echo triple inversion recovery sequences (3D STIR) for diagnosing myocardial oedema in individuals with suspected early myocarditis and at follow-up. A total of 16 individuals with suspected myocarditis and 15 controls matched for gender and age were studied prospectively. An electrocardiogram-triggered T1 and T2 mapping with a gradient spin echo technique and 3D STIR sequences were utilised to cover the entire left ventricle for the evaluation of oedema. The study distinguished a significantly higher global signal intensity ratio with 3D-STIR in individuals with suspected myocarditis compared with controls, and a significant change during follow-up. There was no significant difference in T1-, T2 mapping between patients and controls, or between the initial examination and follow-up of individuals. It was showed that global 3D-STIR ratio may, therefore, be beneficial for the diagnosis of myocarditis and should be investigated further.
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