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The balance of thrombosis and hemorrhage in STEMI patients with or without associated cardiac arrest: An observational study

Resuscitation Nov 07, 2019

Picard F, Llitjos JF, Diefenbronn M, et al. - Researchers conducted a monocentric, retrospective study of patients with ST-elevation myocardial infarction (STEMI) associated with out-of-hospital cardiac arrest (OHCA) to assess the predictors of 30-day mortality, occurrence of major bleeding (MB), and early stent thrombosis (ST). They included 549 patients treated for STEMI without OHCA and 146 patients for STEMI with OHCA. The analysis revealed a higher-risk of ST and MB among patients treated for STEMI associated with OHCA than those who did not experience cardiac arrest. Anticoagulation therapy and the use of glycoprotein IIb/IIIa inhibitors were the independent predictors of MB in OHCA patients. Age and ST were the independent predictors of mortality in OHCA patients, with a protective effect of new anti-P2Y12 treatments
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