Kamoen V, et al. - Experts produced a novel echocardiographic parameter to grade MR, the average pixel intensity (API) method, based on pixel intensity analysis of the continuous-wave Doppler signal. In consecutive individuals with mitral valve prolapse (MVP) (n = 149), transthoracic echocardiography was prospectively done. In 90% of all individuals with MVP, the API method was discovered to be feasible, which was, in turn, considerably greater than vena contracta width, efficient regurgitant orifice area, and regurgitant volume. During a median follow-up period of 17 months, a total of 44/149 had major adverse cardiac episodes, and the preponderance of events transpired in the holosystolic MVP subgroup. For the prediction of events, the degree of MR severity by the API method was extremely important. In comparison with cutoffs for authorized MR grading parameters, an API cutoff of 111 arbitrary units was described as “severe” MR because of MVP, with overall better sensitivity and specificity. No notable variations in measures of MR severity were discovered on follow-up echocardiography in individuals with no major adverse cardiac episodes during the follow-up period (n = 92). Because of MVP, the API method is auspicious of clinical events and outcomes in MR. Hence, in clinical practice, for grading the severity of MR because of MVP, the API method could be thought of.