Liu X, et al. - In this prospective cohort study involving 42,005 Chinese adults who stroke-free at baseline, researchers examined the associations of lipids and lipid ratios with type-specific stroke, and compared their predictive capacities for stroke occurrence. Subgroups were formed based on stroke subtypes (ischemic, hemorrhagic, and total). Study participants were followed up for an average 3.6 years, during which time 781 participants developed stroke (623 ischemic and 158 hemorrhagic). Findings revealed that, in men, a better prediction of stroke risk could be enabled by total cholesterol (TC)/high-density lipoprotein cholesterol (HDL-C) ratio, whereas, in women, triglyceride (TG) levels offered a better stroke prediction. In both sex, no lipid variables were found to be significantly related to hemorrhagic stroke. Differentiation of high stroke risk individuals could be assisted by TC/HDL-C and TG, which may serve as potential targets for stroke prevention.