Mengel E, et al. - Authors identified the inflammatory markers that most strongly associate with pubertal bone mineral density (BMD) increment in boys with overweight and obesity (OWB). Findings suggested an association of lower increment in BMD in OWB with higher BMI gain and increasing serum vascular endothelial growth factor (VEGF) concentration during pubertal maturation. They noted a significant association of VEGF, epidermal growth factor (EGF), interleukin (IL)-8, and interferon-gamma (IFN-γ) with BMD during pubertal maturation in boys with different BMI values.