Kutsch J, et al. - The N-terminal pro-brain-type natriuretic peptide (NT-proBNP) at rest is known to be associated with prognosis in pulmonary arterial hypertension (PAH). In this current study, researchers looked at the association of NT-proBNP values at rest and during peak exercise with hemodynamics and cardiopulmonary exercise testing parameters in therapy-naive PAH patients. They found that ΔNT-proBNP (NT-proBNP level at exercise minus NT-proBNP level at rest) did not contribute to a better assessment of disease severity in PAH.