Ganti A, Kuhar HN, Eggerstedt M, et al. - In this investigation involving 177 patients, researchers intended to determine if there is a connection between serum eosinophilia, defined as > 6.0% (> 0.60 th/μL), and structured histopathology in chronic rhinosinusitis (CRS). In order to analyze sinus tissue removed during functional endoscopic sinus surgery, a structured histopathology report of 13 variables was utilized. According to findings, CRS patients with serum eosinophilia showed severe disease burden on histopathology with elevated rates of polypoid disease and tissue eosinophilia. However, eosinophilic disease on histopathology has been demonstrated by a large number of patients without serum eosinophilia, suggesting that preoperative serum eosinophilia alone can not be accurately used to predict eosinophilic CRS.