Loef M, Ioan-Facsinay A, Mook-Kanamori DO, et al. - Researchers conducted this population-based NEO study to examine the relationship of postprandial and fasting plasma saturated fatty acid (SFAs), monounsaturated fatty acid (MUFAs) and polyunsaturated fatty acid (PUFAs) concentrations with hand and knee osteoarthritis (OA). By AUSCAN and KOOS, respectively, hand and knee pain was determined. Of the 5,328 candidates (mean age 56 years), 7% were listed as hand OA, 10% as knee OA and 4% as hand and knee OA. Findings suggested a positive association of plasma postprandial SFA and PUFA levels with clinical hand and structural knee OA in men, but not in women. Compared with postprandial concentrations, association of fasting fatty acid concentrations were weaker.