The association of physical activity and depression in patients with, or at risk of, osteoarthritis is captured equally well by patient-reported outcomes (PROs) and accelerometer measurements - Analyses of data from the osteoarthritis initiative
Seminars in Arthritis and Rheumatism Jun 05, 2019
der Zee-Neuen A, et al. - Given the increased risk of depression among osteoarthritis (OA) patients, and low levels of physical activity (PA) as potential warning sign of depression, researchers evaluated PA estimated by patient reported outcomes (PROs) vs measured with accelerometers (ACCs) for capturing depression in patients with, or at risk of, OA. They cross-sectionally analyzed 48-months data from the Osteoarthritis Initiative. Outcome (depression y/n) comprised the dichotomized Centre for Epidemiological Studies Depression Scale score. PRO was determined using the Physical Activity Scale for the Elderly (PASE). Average minutes of daily moderate to vigorous activity were included in ACC-data. Outcomes revealed the similar performance of PRO and ACC data in capturing depression. Indirect comparison even pleads for PROs. The PASE was supported as an appropriate alternative to screen for depression in OA patients given the costs of accelerometers and the additional burden for patients.
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