• Profile
Close

The association of paternal IQ with autism spectrum disorders and its comorbidities: A population-based cohort study

Journal of the American Academy of Child & Adolescent Psychiatry Apr 27, 2019

Gardner RM, et al. – In this study, researchers investigated the link between paternal intelligence and autism spectrum disorder (ASD), considering co-occurring intellectual disability (ID) and attention-deficit hyper-activity disorder (ADHD), via a register-based cohort study design that included over 360,000 individuals with fathers conscripted to the Swedish military, resident in Stockholm, Sweden, born 1984-2008, and followed until December 31, 2011 for diagnosis of ASD, ADHD, and/or ID. In models adjusted for individual and family characteristics, high paternal IQ was noted to be correlated with offspring risk of ASD without ID/ADHD—an association that appeared to be driven largely by the fathers’ scores on the technical comprehension portion of the test. Conversely, an association of low paternal IQ with ASD+ID and ASD+ADHD was noted; low paternal IQ was strongly associated with ID and present also for ADHD without co-occurring ASD or ID. Association of paternal IQ to offspring risk of ASD was non-monotonic. The presence of co-occurring disorders was found to influence this association. Overall, phenotypic diversity among affected individuals was suggested, according to findings.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay