van Steen SC, et al. - The impact of intravenous insulin and glucose infusion on intensive care unit (ICU) and hospital mortality was determined in this retrospective association study. Using data from all patients admitted to a medical-surgical ICU between January 2012 and September 2017, they included 3,966 cases. Observations suggest an correlation between intravenous insulin administration an increased risk of ICU and hospital mortality, after adjustment for potential confounders. Although a limited amount of parenteral glucose administration was done, it remained correlated with ICU mortality. However, these results do not clarify if this association is an epiphenomenon, or represents true harm of insulin and glucose administration.