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The association of abnormal liver tests with hepatitis C testing in primary care

American Journal of Medicine Aug 02, 2019

Schreiner AD, Bian J, Zhang J, et al. - In in 4,512 patients with persistently abnormal liver tests, researchers assessed if abnormal liver chemistries and other clinical and demographic factors are correlated with hepatitis C antibody (HCV Ab) testing. Within 1 year of the second abnormality, only 730 had HCV Ab testing and HCV Ab was detected in 81 out of 730. Greater odds of HCV Ab testing correlated with mixed and hepatocellular patterns of a liver test abnormality, female gender, alcohol, and tobacco abuse. Higher odds of positive HCV Ab outcomes were observed in hepatocellular and mixed patterns of liver test abnormalities, male gender, Medicaid enrollment, and drug and tobacco abuse. Therefore, in individuals with consecutively raised liver tests, there was a chance to improve hepatitis C diagnostic testing; hepatocellular and mixed patterns of abnormality should induce action in primary care providers.

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