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The association between tuberculosis and the development of insulin resistance in adults with pulmonary tuberculosis in the Western sub-district of the Cape Metropole region, South Africa: A combined cross-sectional, cohort study

BMC Infectious Diseases Aug 24, 2017

Philips L, et al. – Researchers performed this work to assess whether an association existed between tuberculosis (TB) and insulin resistance (IR) development in adults with newly diagnosed pulmonary tuberculosis at baseline. In addition, they documented changes in IR status during TB follow–up periods. In newly diagnosed pulmonary tuberculosis patients, findings revealed an association between tuberculosis and IR development. Although not significant, a decrease in IR levels was observed over time, which could be indicative of a clinical improvement. A high prevalence of IR amongst young tuberculosis patients, therefore, suggested the necessity for early identification in order to facilitate a reversal of IR and prevent possible IR–related complications.
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