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The association between threatened preterm labour and perinatal outcomes at term: A population‐based cohort study

BJOG: An International Journal of Obstetrics and Gynaecology May 13, 2021

Gagnon LC, Allen VM, Crane JM, et al. - A population‐based cohort study was performed to determine the relationship between threatened preterm labour (TPTL) and perinatal outcomes of infants born at term in Nova Scotia, Canada. In this study, 2,278 (0.9%) involved TPTL out of 256,599 term deliveries. TPTL was characterized as pregnancies with a hospital admission between 20 and 37 weeks of gestation, with a diagnosis code denoting TPTL with the administration of antenatal corticosteroids, or with the administration of any tocolysis using data from the Nova Scotia Atlee Perinatal Database. Researchers used Poisson regression models to calculate the risk ratios with 95% CI of maternal and perinatal outcomes in women who had an episode of TPTL relative to those who did not. The outcomes suggested that the affected pregnancies are at increased risk for adverse perinatal outcomes, although the prevalence of TPTL in term deliveries is low. As per the findings, elevated fetal surveillance should be considered in the management of pregnancies affected by TPTL.

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