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The association between pre-pregnancy impaired fasting glucose and adverse perinatal outcome

Diabetes Research and Clinical Practice Apr 02, 2018

Salman L, et al. - The tie-up between impaired fasting glucose (IFG) prior to pregnancy with maternal and neonatal outcome was analyzed among singleton deliveries in a single, tertiary, university-affiliated medical center between August 2007 and December 2012. Inclusion criteria involved women who had a fasting glucose test done up to 26 weeks prior to pregnancy. Women with diabetes mellitus and women carrying a fetus with structural or chromosomal anomalies were excluded. The multivariable logistic regression disclosed that pre-pregnancy IFG exhibited a prominent and an independent connection with mild preeclampsia. It was also inferred that pre-pregnancy IFG was related to increased risk for abnormal glucose challenge test and gestational diabetes. It served as an independent risk factor for adverse pregnancy outcome including mild preeclampsia.
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