Kuchibhatla M, et al. – Due to the small but growing body of evidence supporting a relationship between neighborhood socioeconomic status (NSES) and cognitive decline, researchers examined 8,198 individuals from the 1992–2010 waves of the Health and Retirement Study (HRS) for cognitive decline in association with NSES, and cardiovascular and cerebrovascular risk factors (heart disease, diabetes, hypertension, and stroke). The three-quadratic-class model best fit the data, where higher classes signified superior cognitive ability. Younger white females primarily represented the demographic group with better cognitive function. Those in the highest quartile of NSES displayed 57% higher odds of being in the high cognitive function class. The odds having of lower cognitive function were higher for heart disease, diabetes, hypertension, and stroke. Findings suggested persistence of neighborhood socioeconomic status, cardiovascular risk, and cerebrovascular risk across the cognitive trajectory classes.