The association between hysterectomy and ovarian cancer risk: A population-based record-linkage study
Journal of the National Cancer Institute Feb 18, 2019
Dixon-Suen SC, et al. - Researchers analyzed linked electoral, hospital, birth, death, and cancer records for thenfemale adult Western Australian population (837,942 women) over a 27-year period, to examine the link between hysterectomy and ovarian cancer risk. They studied this association overall and by age at hysterectomy, time period, surgery type, and indication for hysterectomy. Using cancer registry records, they determined 1,640 ovarian cancer diagnoses. They assessed ovarian cancer incidence in relation to hysterectomy by using Cox regression and by estimating hazard ratios (HRs) and 95% confidence intervals (CIs). Risk of developing ovarian cancer in most of the women was not likely to be modified substantially by having a hysterectomy with ovarian conservation. While decision making regarding surgical management of endometriosis or fibroids, ovarian cancer risk attenuation could be taken as a possible benefit of hysterectomy, but only if confirmed.
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