Azami M, et al. - Based on PRISMA Guideline, researchers conducted a systematic review and meta-analysis to examine the association between gestational diabetes and postpartum depression. Via searching all the relevant epidemiological studies in international databases of Scopus, PubMed, Science Direct, Embase, Web of Science, CINAHL, Cochrane, EBSCO, and Google scholar search engine using the MeSH Keywords in English without time limit, a total of 18 studies have been reviewed with a sample size of 2,370,958. Findings suggested that gestational diabetes can be a risk factor for postpartum depression. Therefore, it seems necessary to examine postpartum depression in pregnant women with gestational diabetes.