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The association between fasting plasma glucose and glycated hemoglobin in the prediabetes range and future development of hypertension

Cardiovascular Diabetology May 02, 2019

Geva M, et al. - In a large cohort of normotensive subjects (n=5,016) without diabetes mellitus or other cardiovascular risk factors, researchers assessed the development of hypertension (HTN) in relation to both fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) levels in the prediabetes range. They classified participants into normoglycemic and prediabetic groups. Findings revealed an independent and significant association of FPG in the prediabetes range, albeit not of glycated hemoglobin, with future development of HTN. For HTN development, impaired fasting glucose was shown to have a pivotal predictive role whereas abnormal HbA1c levels had a limited independent role.

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