Hosokawa Y, Okada M, Suemori K, et al. - In this retrospective analysis, researchers investigated if and how ear involvement could impact clinical features as well as prognosis of AAV (ANCA-associated vasculitis). Participants included 36 patients diagnosed with otitis media with ANCA-associated vasculitis (OMAAV) and 44 patients diagnosed with AAV without ear involvement (non-OMAAV). Findings revealed no differences in serological measurements of disease activity between the groups. However, patients with AAV with ear involvement significantly more commonly had eye involvement, facial palsy, and hypertrophic pachymeningitis. Additionally, kidney was involved less commonly and renal impairment was milder in AAV cases with ear involvement. These observations can be considered clinical characteristics. AAV with ear involvement was associated with a significantly higher relapse rate.