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The association between baseline and 3-month albuminuria and 1-year prognosis of ischemic stroke

Cerebrovascular Diseases Aug 31, 2021

Wang D, Pan Y, Li H, et al. - The results demonstrate that in Chinese ischemic stroke patients, changes in albuminuria can predict adverse 1-year outcomes. It was shown that persistent albuminuria was independently correlated with 1-year all-cause death, stroke recurrence, and poor functional outcome.

  • Researchers recruited a sum of 5,311 patients in the study.

  • As per the findings, 3,738 (70.4%), 483 (9.1%), 451 (8.5%), and 639 (12.0%) patients were reported with no albuminuria, baseline albuminuria, 3-month albuminuria, and persistent albuminuria, respectively.

  • Persistent albuminuria was independently correlated with all-cause death (hazard ratio [HR], 2.23; 95% CI, 1.17–4.25; p = 0.02), stroke recurrence (HR, 1.55; 95% CI, 1.02–2.36; p = 0.04), and poor functional outcome (OR, 2.22; 95% CI, 1.66–2.96; p < 0.001) after adjustment for confounding variables.

  • The results showed that baseline albuminuria was independently correlated with poor functional outcome (OR, 1.65; 95% CI, 1.19–2.28; p = 0.003), while 3-month albuminuria was independently correlated with stroke recurrence (HR, 1.68; 95% CI, 1.06–2.65; p = 0.03).

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