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The adjusted global antiphospholipid syndrome score (aGAPSS) and the risk of recurrent thrombosis: Results from the APS ACTION cohort

Seminars in Arthritis and Rheumatism Jun 05, 2019

Radin M, et al. - Researchers examined adjusted Global AntiphosPholipid Syndrome Score (aGAPSS) of patients with antiphospholipid syndrome (APS) and history of recurrent thrombosis vs patients without recurrent thrombosis. In this cross-sectional study of 379 antiphospholipid antibody (aPL)-positive patients who presented with arterial and/or venous thrombosis, patients with recurrent thrombosis (arterial or venous) showed significantly higher aGAPSS compared to those without recurrence (7.8 ± 3.3 vs 6 ± 3.9). Patients with recurrent arterial, but not venous, thrombosis showed higher aGAPSS (8.1 ± SD 2.9 vs. 6 ± 3.9) when the analysis was done on the basis of site of the recurrence. These findings suggest the possible utility of aGAPSS in risk stratifying patients based on the likelihood of developing recurrent thrombosis in APS.
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