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The addition of intrathecal morphine to a transversus abdominis plane block with liposome bupivacaine provides more effective analgesia than transversus abdominis plane block with liposome bupivacaine alone: A retrospective study

Local and Regional Anesthesia Mar 01, 2019

Hutchins JL, et al. - Whether the benefit of intrathecal morphine (ITM) in patients after undergoing a cesarean section has been eliminated by standardization of using liposomal bupivacaine in transversus abdominis plane (LB TAP) blocks, was investigated in this retrospective review of 358 patients who had cesarean section over an 11-month period. A total of 67 patients received only an LB TAP and were compared to 291 patients who were administered an LB TAP and ITM. Under ultrasound guidance, bilateral placement of all blocks was implemented following closure of the surgical incision, and morphine was added to the spinal used for the case. Compared to those who received an LB TAP alone, less consumption of opioids in the first 24 hours and overall was reported in patients who received ITM in addition to an LB TAP block. This was suggestive of an analgesic role of ITM in patients who have also received an LB TAP block as a part of their multimodal pain regimen for cesarean sections.
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