The added value of fasting blood glucose to serum squamous cell carcinoma antigen for predicting oncological outcomes in cervical cancer patients receiving neoadjuvant chemotherapy followed by radical hysterectomy
Cancer Medicine Jul 22, 2019
Wu MF, et al. - In this retrospective review of patients (n=347) taking neoadjuvant chemotherapy (NACT) for locally advanced cervical cancer (LACC), researchers investigated the value of the combination of fasting blood glucose (FBG) with squamous cell carcinoma antigen (SCCA) evaluations in the prediction of tumor responses to chemotherapy and pretreatment prognostication. According to the findings, an acceptable prediction of complete response post-NACT was enabled by SCCA, FBG, and a combination of SCCA and FBG. The identified independent prognostic factors were pretreatment SCCA and FBG levels. A refined prognostic stratification of LACC patients was achieved with the combination of SCCA and FBG levels, this permitted the detection of patients with the highest risk of recurrence and death.
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