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TGF-β1 alters esophageal epithelial barrier function by attenuation of claudin-7 in eosinophilic esophagitis

Mucosal Immunology Aug 28, 2017

Nguyen N, et al. – An analysis was formulated to ascertain the role of transforming growth factor-β1 (TGF-β1) in the epithelial barrier in models of eosinophilic esophagitis (EoE). Based on the data obtained, it was reported that through claudin-7 (CLDN7) dysregulation, TGF–β1 participated in esophageal epithelial barrier dysfunction
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