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TET1 inhibits EMT of ovarian cancer cells through activating Wnt/β-catenin signaling inhibitors DKK1 and SFRP2

Gynecologic Oncology Sep 05, 2017

Duan H, et al. – Study's aspiration was to illustrate the role of Ten–eleven translocation 1 (TET1) in epithelial ovarian cancer (EOC) development. By activating Wnt/β–catenin signaling inhibitors Dikkopf 1 (DKK1) and secreted Fzd receptor protein 2 (SFRP2), TET1 had potent tumor–suppressive effects in EOC.
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