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Term complications and subsequent risk of preterm birth: Registry based study

BMJ May 04, 2020

Kvalvik LG, Wilcox AJ, Skjærven R, et al. - Via performing a population based, prospective register based study, researchers sought to determine conditions and outcomes of a first delivery at term that might predict later preterm birth. Medical Birth Registry of Norway, 1999-2015, yielded data of 302,192 women giving birth (live or stillbirth) to a second singleton child between this time period. Per analyses, women with history of preeclampsia, placental abruption, stillbirth, neonatal death, or small for gestational age in a first term pregnancy are at substantially increased risk of subsequent preterm delivery. This suggests sharing of important underlying causes between term complications and preterm delivery that persist from pregnancy to pregnancy and are perhaps related with a mother’s predisposition to disorders of placental function.

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