Temporal variation of staphylococcus aureus clonal complexes in atopic dermatitis: A follow up study
British Journal of Dermatology Aug 10, 2018
Clausen ML, et al. - In atopic dermatitis (AD) patients, authors examined the temporal variations in S. aureus colonization and S. aureus CC-type and linked them to disease severity, skin barrier properties and filaggrin (FLG) gene mutations. They categorized patients on disease severity (SCORAD), skin barrier properties (TEWL, pH) and FLG gene mutations. Findings suggested an association of temporal variation of S. aureus CC-type with the flares of the disease. In patients colonized at both visits, significantly higher skin pH was found, while they did not note a relationship between change in CC-type and TEWL, pH or FLG gene mutations.
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