Temporal trends in statin prescriptions and residual cholesterol risk in patients with stable coronary artery disease undergoing percutaneous coronary intervention
The American Journal of Cardiology May 13, 2019
Guedeney P, et al. - In this single-center study with prospectively enrolled patients who underwent elective percutaneous coronary intervention (PCI) between January 2010 and May 2016, researchers assessed the rates of adherence to guideline-recommended statin therapy (GRST) and residual cholesterol risk (RCR) at follow-up post-PCI. Of 2,653 patients included, 1,304 (49.2%) were discharged with GRST. Female gender, previous myocardial infarction, smoking, and higher low-density lipoprotein cholesterol (LDL-C) level at baseline were identified as risk factors of RCR at follow-up. An increased adjusted risk of mortality within 1 year of the second LDL-C measurement was reported in relation to the presence of RCR. A significant increase in the rate of GRST at discharge was reported over time in patients who underwent elective PCI (from 44.2% in 2010 to 63.0% in 2016) but no appreciable change was evident in the prevalence of RCR at follow-up.
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