Krysko KM, Henry RG, Cree BAC, et al. - In this observational cohort study, researchers ascertained if biological aging as measured by leukocyte telomere length was correlated with clinical disability and brain volume loss in multiple sclerosis (MS). The study sample consisted of people aged 18 to 65 years meeting diagnostic criteria for MS or clinically isolated syndrome at the University of California, San Francisco. Participants in the study were 356 women and 160 men (mean age was 43 years). According to findings, shorter telomere length was linked to disability independent of chronological age, indicating that biological aging can lead to MS neurological injury. Targeting aging-related mechanisms was a possible therapeutic strategy against the progression of MS.