Target doses of secondary prevention medications are not being achieved in patients with reduced LV systolic function after acute coronary syndrome (ANZACS-QI 34)
Heart, Lung, and Circulation Apr 17, 2020
Chan D, et al. - Researchers investigated the dispensing and uptitration of angiotensin converting enzyme inhibitors (ACEi), angiotensin II receptor blockers (ARB) and beta blockers after acute coronary syndrome (ACS), according to left ventricular ejection fraction. From the All New Zealand Acute Coronary Syndrome Quality Improvement (ANZACS-QI) registry, they assessed 4,082 patients who presented with ACS and underwent coronary angiography during 2015. Of these, 602 (15%) had reduced ejection fraction (rEF). Observations revealed suboptimal dispensing of evidence-based medications in the year following ACS. Requirement of further intervention is identified to improve medication uptitration and adherence, especially of beta blockers and ACEI/ARBs in cases with reduced ejection fraction.
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