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Systolic characteristics and dynamic changes of the mitral valve in different grades of ischemic mitral regurgitation – insights from 3D transesophageal echocardiography

BMC Cardiovascular Disorders May 18, 2018

Morbach C, et al. - Using three-dimensional (3D) transesophageal echocardiography (TEE), geometric and dynamic changes of the mitral valve (MV) were compared between patients with significant and mild ischemic mitral regurgitation (IMR), focusing on structural and functional mitral valve leaflet and annular characteristics. In patients with significant IMR, a spatio-temporal alteration of the mitral valve coaptation line due to a delayed increase in active-anterior-leaflet-area was noted. In these subjects, a significant enlargement and loss in motility of the MV annulus were also detected. Likely contribution of this abnormality to IMR severity was suggested and therefore, is worth the evaluation of becoming a parameter for clinical decision-making. Addressing the leaflets aiming to increase the active leaflet-area is a promising therapeutic approach for significant IMR.

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