Lan L et al. – The systematic review and meta-analysis evaluated the impact of preconception lifestyle interventions on live birth, birth weight, and pregnancy rate. The authors concluded that lifestyle interventions demonstrated benefits for weight loss and increased natural pregnancy rate, but not for live birth or birth weight.

Methods

• Published literature search to identify studies including non-pregnant women of childbearing age intent on conceiving or their male partners.

Results

• Following screening of 1802 articles, 8 studies were analyzed; overweight or obese subfertile women seeking reproductive assistance, including few community-based studies were included and no studies included men.
• Greater reduction in weight and BMI was reported with intervention.
• An increased natural pregnancy rate was the only significant fertility outcome reported.
• There were no observed differences for ART adverse events, clinical pregnancy, pregnancy complications, delivery complications, live birth, premature birth, birth weight, neonatal mortality, or anxiety.