Qu R, Tu D, Ping W, et al. - Researchers retrospectively examined the electronic medical records of patients with surgically resected multiple lung cancer between February 2016 and July 2019, focusing on the clinical features and prognosis of patients with lymph node metastasis (LNM) and different epidermal growth factor receptor (EGFR) mutations. They diagnosed 125 individuals with synchronous multiple lung cancers (SMLC), though only 8 patients had LNM and different EGFR mutations. This study’s findings demonstrate the clinical utility of EGFR detection in SMLC, particularly in patients with LNM. According to the findings, SMLC with LNM and different EGFR mutations should be considered multiple primary lung cancers rather than intrapulmonary metastases. Because prognosis is good, comprehensive treatment based on surgery may be preferable in these patients.