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Survival, prevalence, progression and repair of abdominal aortic aneurysms: results from three randomised controlled screening trials over three decades

Clinical Epidemiology Jan 30, 2020

Lindholt JS, Diederichsen AC, Rasmussen LM, et al. - Researchers intended to correlate survival, prevalence, and repair rate of abdominal aortic aneurysms (AAA) in Denmark in the 1990s, the 2000s, and the 2010s – and to measure any variance in factors known to affect the prevalence. They collected baseline status and up to 5-year outcomes of 34,079 general population men aged 65– 74 from three RCTs; the Viborg study (1994– 1998, n=4,860), the Viborg Vascular (VIVA) trial (2008– 2011, n=18,748), and the Danish Cardiovascular (DANCAVAS) trial (2015– 2018, n=10,471). They compared the Danish prevalence of AAA today with the nineties. The data showed that unchanged aneurysmal progression rates combined with improved survival of men at risk of AAA leave them in a long time to generate an AAA, be diagnosed and to require later aneurysmal repair or experience rupture.
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