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Survival impact of treatment delays in surgically managed oropharyngeal cancer and the role of human papillomavirus status

Head & Neck May 30, 2019

Goel AN, et al. - Researchers examined how treatment delays influence survival in oropharyngeal cancer. In addition, they sought to determine whether or not human papillomavirus (HPV) status influence the effect. From the National Cancer Database, patients with resected oropharyngeal cancer who underwent adjuvant radiation from 2010 to 2014 had optimal thresholds of 30, 40, and 51 days for diagnosis to surgery (DTS), surgery to radiation, and duration of radiation, respectively. Outcomes revealed a significant impact of treatment delays on survival in oropharyngeal cancer. HPV-negative vs HPV-positive disease seemed to be related to stronger consequences of prolonged DTS.
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