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Survival by race in men with chemotherapy-naïve enzalutamide- or abiraterone- treated metastatic castration-resistant prostate cancer

Prostate Cancer & Prostatic Diseases Nov 06, 2021

George DJ, Ramaswamy K, Huang A, et al. - Using claims data from the Veterans Health Administration (VHA) database, researchers examined overall survival (OS) by race in men who received treatment with enzalutamide or abiraterone (novel hormonal therapy [NHT]) for chemotherapy-naïve metastatic castration-resistant PC (mCRPC).

  • A total of 2,910 patients were identified (787 Black, mean 71.7 years; 2,123 White, mean 74.0 years) by diagnosis codes, evidence of surgical/medical castration, and a prescription claim for enzalutamide or abiraterone after castration from April 2014–March 2017.

  • Better outcomes were recorded for black men with chemotherapy-naïve mCRPC initiating NHT when compared with similarly treated white men.

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