Tejera-Vaquerizo A, et al. - In a large multicenter cohort of melanoma patients (n=4249) studied in this observational study, researchers investigated prognostic factors for thin melanoma and predictors and prognostic value of sentinel lymph node (SLN) involvement. For melanoma-specific survival, SLN status was identified as the most significant prognostic factor, followed by sex, ulceration, and Clark level for patients who underwent sentinel lymph node biopsy. The only factor that was related to a positive SLN biopsy was a mitotic rate of >2 mitoses/mm². Findings revealed a link between a high mitotic rate and metastatic SLN involvement. In thin melanoma cases with a high mitotic rate, discussing and advising SLN biopsy was supported.