Surgical treatment of “intermediate risk” lymph node negative cervical cancer patients without adjuvant radiotherapy—A retrospective cohort study and review of the literature
Gynecologic Oncology Oct 25, 2018
Cibula D, et al. - Researchers sought to report the oncological outcome of “intermediate risk” lymph node negative cervical cancer patients treated by tailored surgery without adjuvant radiotherapy. Data from two institutions that refer these patients for adjuvant radiotherapy served as a control group. They analyzed patients with stage IB cervical cancer treated with radical hysterectomy and pelvic lymphadenectomy, who had negative pelvic lymph nodes, but a combination of negative prognostic factors adopted from the GOG 92 trial. In stage IB lymph node-negative cervical cancer patients with negative prognostic factors, both radical surgery or combined treatment leads to an excellent oncological outcome, especially local control. More accurate pre-operative and pathological staging and an improvement in surgical techniques may explain the substantially better outcome than in the GOG 92 trial.
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