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Surgical resection and survival outcomes in metastatic young adult colorectal cancer patients

Cancer Medicine Jun 20, 2021

Arhin ND, Shen C, Bailey CE, et al. - Researchers assessed survival advantage of surgical resection (primary and/or metastatic) vs palliative therapy among 6708 young adults aged 18–45 years diagnosed with metastatic colorectal cancer (mCRC). The participants were selected from the Surveillance, Epidemiology, and End Results database. The median overall survival (OS) was estimated to be 36 months for patients who received both primary tumor resection and metastasectomy vs 13 months for those who did not receive any surgical intervention. In this largest observational analysis assessing survival results in young-onset mCRC cases and the role of surgical intervention of the primary and/or metastatic site, experts found evidence that surgical intervention of the primary and/or metastatic site resulted in a statistically significant increase in OS among young mCRC patients.

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