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Suppressed expression of CXCL14 in hepatocellular carcinoma tissues and its reduction in the advanced stage of chronic HBV infection

Cancer Management and Research Dec 18, 2019

Lin Y, et al. - This study was conducted on 212 individuals with chronic HBV infection and 180 HBV-free controls to examine the correlation between CXCL14 (a significantly under-expressed mRNA in hepatocellular carcinoma tissues as well as head and neck squamous cell carcinoma and cervical squamous cell carcinoma) polymorphisms and HBV progression as well as liver function parameters. In HBV-related HCC tissues, CXCL14 was considerably suppressed, and its polymorphisms were associated with advanced-stage chronic HBV infection and impaired liver function.
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