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Superficial macular vessel density in eyes with mild, moderate, and severe primary open-angle glaucoma

Graefe's Archive for Clinical and Experimental Ophthalmology Feb 25, 2021

Huo Y, Thomas R, Guo Y, et al. - Researchers conducted this cross-sectional study to report changes in and associations of macular vessel density (VD) and perfusion density (PD) using optical coherence tomography angiography (OCTA) in mild, moderate, and severe open-angle glaucoma. The sample consisted of 133 patients with open-angle glaucoma (133 eyes: 47 mild, 33 moderate, and 53 severe glaucoma) and 73 normal individuals (right eyes). All participants underwent Cirrus OCTA measurements. In mild and severe glaucoma, macular microcirculation significantly decreased. No substantial difference between mild and moderate glaucoma has been found. Age, severe MD, lower SS, and thinner mGCIPL thickness were independently linked to decreased macular VD.

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