Parvinian A, et al. - The clinicians performed this study to ascertain the efficacy of ¹¹C-choline PET/CT for the detection of parathyroid adenomas by retrospectively reviewing a large patient population. ¹¹C-choline PET/CT identified parathyroid adenomas with high specificity in this patient population. The prospective investigation was warranted to validate this outcome and delineate the utility of ¹¹C-choline PET/CT relative to other modalities.