Sørensen JO, Rasmussen A, Roesbjerg T, et al. - Youth treated with selective serotonin reuptake inhibitors (SSRIs) commonly experience suicidality.

• A within-subject study design was used in this observational, longitudinal, retrospective study of patients (aged 0-17 years) treated with SSRIs for primarily depression, anxiety or obsessive-compulsive disorder.

• In the weeks following SSRI initiation, there was a decrease in the proportion of patients with overall suicidality and stability in the proportion with attempted suicide.

• For suicidality during SSRI treatment in youth, important predictors include previous suicidality, depression, female gender, and previous non-suicidal self-injury.