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Sudden unexpected death in epilepsy in children: A focused review of incidence and risk factors

Journal of Neurology, Neurosurgery & Psychiatry Apr 15, 2018

Saxena A, et al. - Researchers undertook a focused narrative review of available studies on paediatric sudden unexpected death in epilepsy (SUDEP) to comprehend its risk factors and to develop strategies to recognize and where possible modify SUDEP risk and ultimately reduce incidence. This review yielded uncontrolled seizures to be the prime risk factor. Findings supports the view that in reducing adult mortality related to SUDEP, children entering adolescence with optimal seizure control could be a key aspect. Predicting prospective, individualised SUDEP risk was noted to be challenging due to a myriad of risk factors and an inherent non-homogeneous paediatric epilepsy population. However, this review supported the existence of an adequate evidence base to support information giving and communication to support young people with epilepsy and their families in being active partners in recognizing and reducing their SUDEP risk.
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