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Successful treatment of a cohort of infants with neonatal diabetes using insulin pumps including data on genetics and estimated incidence

Acta Pediatrica Jan 08, 2020

Torbjörnsdotter T, et al. - Since neonatal diabetes is rare, and treatment is challenging, researchers conducted this prospective cohort study to present aspects on treatment, genetics, and incidence, as well as to compare with data from the National Diabetes Registry, the Neonatal Quality Register and the National Patient Register. Seven infants were treated, five of them boys, in the 19-year study period January 1, 1998, to December 31, 2016. Data reported that neonatal diabetes incidence was 2/100,000, higher than previously estimated for Europe. The registries reported similar but lower incidences. The ability of the pump to deliver small doses of insulin and the size, length and insertion angle of cannulas and tubing were the most important practical characteristics. The authors concluded that insulin pumps in neonatal diabetes were safe. All seven cases have been transient.
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